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Tuesday, August 4, 2020 | History

3 edition of Health-based recommended occupational exposure limits for ethyl methanesulphonate (EMS), methyl methanesulphonate (MMS) found in the catalog.

Health-based recommended occupational exposure limits for ethyl methanesulphonate (EMS), methyl methanesulphonate (MMS)

Netherlands. Werkgroep van Deskundigen ter Vaststelling van MAC-Waarden.

Health-based recommended occupational exposure limits for ethyl methanesulphonate (EMS), methyl methanesulphonate (MMS)

by Netherlands. Werkgroep van Deskundigen ter Vaststelling van MAC-Waarden.

  • 349 Want to read
  • 32 Currently reading

Published by Directorate-General of Labour in Voorburg, The Nederlands .
Written in English

    Subjects:
  • Ethyl methanesulfonate -- Threshold limit values.,
  • Methyl methanesulfonate -- Threshold limit values.

  • Edition Notes

    StatementDutch Expert Committee for Occupational Standards.
    ContributionsNetherlands. Directoraat-Generaal van de Arbeid.
    Classifications
    LC ClassificationsRA1242.M38 N48 1989
    The Physical Object
    Paginationii, 57 p. ;
    Number of Pages57
    ID Numbers
    Open LibraryOL1949567M
    ISBN 109053070354
    LC Control Number90174807

    In several instances, quantitative interpretation of mutagenicity dose–response data has been used for risk assessment and regulatory decision‐making. For example, in , a batch of the AIDS drug Viracept became contaminated with a genotoxic carcinogen, ethyl methanesulfonate (EMS; Müller and Cited by: 4.   DECOS (Dutch expert committee for occupational standards) Health-based recommended occupational exposure limits for Ethyl Methanesulphonate (EMS) and Methyl Methanesulphonate (MMS) Voorburg: Directorate-General of Labour;

    DECOS (Dutch expert committee for occupational standards): Health-based recommended occupational exposure limits for Ethyl Methanesulphonate (EMS) and Methyl Methanesulphonate (MMS). Voorburg: Directorate-General of Labour; Chemical Carcinogenesis Research Info System (CCRIS) , Ethyl methanesulphonate, CAS: Occupational Exposure Limits (OELs) for Chemical Substances Ethylene glycol monobutyl ether [CAS No. ], or 2-butoxyethanol, is a colorless liquid at room temperature (boiling temperature °C; saturated vapor pressure mmHg (20°C)) with a gentle odor and is used as a solvent for paints, print inks, dyes, detergents, brake Author: Kenichi Azuma, Ginji Endo, Yoko Endo, Tetsuhito Fukushima, Kunio Hara, Hajime Hori, Seichi Horie, Hy.

    ETHYL TOLUENE undergoes vigorous reactions, sometimes amounting to explosions, with strong oxidizing agents. Can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), .   Exposure monitoring by personal diffusive samplers, biological monitoring of toluene exposure by urinary hippuric acid determination, haematology, serum biochemistry for liver function, and a subjective symptom survey by questionnaire were conducted on male solvent workers. They were exposed to a mixture of solvents including toluene (geometric mean 18 ppm), methyl ethyl ketone Cited by:


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Health-based recommended occupational exposure limits for ethyl methanesulphonate (EMS), methyl methanesulphonate (MMS) by Netherlands. Werkgroep van Deskundigen ter Vaststelling van MAC-Waarden. Download PDF EPUB FB2

Recommended Health-Based Limits in Occupational Exposure to Selected Organic Solvents: Report of a WHO Study Group (World Health Organization Technical Report Series; ) [WHO Expert Committee] on *FREE* shipping on qualifying offers. The exposure limits will be developed separately by each country according to the different national policies.

This document on the health effects of occupational exposure to 2-ethylhydroxymethyl-1,3-propanediol (trimethylolpropane) is the sixth product of that : Paperback.

* Breathing Ethyl Methanesulfonate can irritate the nose and throat. * High or repeated exposure to Ethyl Methanesulfonate may cause nausea, vomiting and drowsiness. Chronic Health Effects The following chronic (long-term) health effects can occur at some time after exposure to Ethyl Methanesulfonate and can last for months or years: Cancer Hazard.

1 ppm = mg/m 3. ppm [10%LEL] Exposure Limits. TWA ppm ( mg/m 3) TWA ppm ( mg/m 3) Measurement Methods. See: NMAM or OSHA Methods. Physical Description.

Clear, colorless liquid with a weak, ethereal, vinous odor. Molecular Weight. Ionization Potential. Specific Gravity. Upper Exposive Limit. Lower Explosive Limit. Recommended health-based limits in occupational exposure to selected organic solvents.

Report of a WHO Study Group, Geneva, June Author(s): WORLD HEALTH ORGANIZATION. Book: Technical Report Series. In addition, OSHA has separate substance-specific standards, which can be found in the "Notes" section of the "Exposure Limits" table.

Other OSHA standards that generally apply to hazardous substances include the Hazard Communication standard () and the Respiratory Protection standard. ETHYL METHANESULFONATE alkylates nucleophiles such as hydroxy, amino and sulfhydryl groups in model and biological materials.

Is hydrolyzed by excess aqueous alkali to non-corrosive and non-toxic products. Is hydrolyzed by water to a highly corrosive product (NTP, ). Recommendation from the Scientific Committee on Occupational Exposure Limits for 2-ethylhexanol March 5 After gavage to rats, 95% of EH was eliminated within 96 h (mostly within 24 h).

About 70% of the administered dose was excreted in urine, 13% in faeces and 11% in expired air. Occupational exposure limits (OELs) are tools to help employers protect the health of those who may be exposed to chemicals in their workplace.

Under the United Kingdom Control of Substances Hazardous to Health (COSHH) Regulations they define adequate control by inhalation. OELs are set by the Health and Safety Commission (HSC) on advice from its Advisory Committee on Toxic Cited by: EH40/ Workplace exposure limits 10 Substance CAS Workplace exposure limit Comments number Long-term exposure Short-term exposure limit (8-hour TWA limit (minute reference period) reference period) ppm mg.m-3 ppm mg.m-3 Acetaldehyde 20 37 50 92 R12, 36/37, 40 Acetic anhydride 2 10 R10, 20/22, 34File Size: KB.

Scientific Committee on Occupational Exposure Limits for Diacetyl 8-hour TWA: ppm ( mg/m3) STEL: ppm ( mg/m³) BLV: Not assigned Additional categorisation: Notation: This evaluation is an update of the SCOEL Recommendation from and is based on. Occupational exposure limits for chemicals Article in Occupational and Environmental Medicine 58(2) March with 26 Reads How we measure 'reads'.

Ethyl methanesulfonate Revision Date Jan Exposure Guidelines This product does not contain any hazardous materials with occupational exposure limitsestablished by the region specific regulatory bodies.

Physical and chemical properties Physical State Liquid Appearance Colorless Odor No information available Odor Threshold No. NIOSH REL — NIOSH’s recommended exposure limit; the recommended exposure limit for an 8- or hour time-weighted average exposure and/or ceiling. OSHA PEL — Occupational Safety and Health Administration ’s permissible exposure limit expressed as a time.

scientific relevance of occupational exposure limits (OELs) for benzene”, ECHA has prepared a proposal for consideration by RAC. The ECHA-proposal is the subject of this Public Consultation. Please note that the final opinion of RAC will be published on ECHA’s website by OSHA established a A permissible limit for occupational exposure to EtO, which is one part EtO per one million parts of air (1 ppm).' This is determined as a time-weighted-average exposure over an eight- hour period.

In addition, OSHA identified an action-level exposure of ppm, averaged over an eight-hour : Dorothy M. Fogg. The process of developing and using occupational exposure limits is a cornerstone of industrial hygiene practice, with a history dating back to the s.

Occupational exposure limits, known as OELs, have not—until recently—evolved enough to reflect the advances in related sciences of toxicology, risk assessment, and exposure assessment.

Occupational exposure limits (OELs) are used as a risk management tool aiming at protecting against negative health effects of occupational exposure to harmful substances.

The systems of OEL development have not been standardized and divergent outcomes have been reported. However some harmonization processes have been initiated, primarily in Cited by:   By applying the common assumptions for exposure through inhalation including 10 m 3 of air breathed during 8h working day (Galer et al., ; Sargent and Kirk ), and an excess risk of would result in an acceptable level of µg/m 3 (rounded to 2 µg/m 3).Cited by: 3.

The document presents a survey of the literature concerning occupational exposure limits for ethyl ether. This chemical has a wide range of uses in the chemical industry, mainly as a solvent and an extraction medium.

Ethyl ether has also been used as an inhalation anesthetic for surgery, but it has largely been replaced in this role by more.

The mouse spot test has been used to assess a number of chemicals Health-based recommended occupational exposure limits for Ethyl Methanesulphonate (EMS) and Methyl Methanesulphonate (MMS) Voorburg: Directorate-General of Labour; Cited by: These thresholds are used in calculating toxicological health-based limits, such as occupational exposure limits (OEL) for DS, when an adequate dataset is available to derive such a limit (Galer et al., ; Sargent and Kirk, ).

In the early stages of pharmaceutical development when only limited preclinical test results are available.Ethylbenzene Hazard Summary Ethylbenzene is mainly used in the manufacture of styrene. Acute (short-term) exposure to ethylbenzene in humans results in respiratory effects, such as throat irritation and chest constriction, irritation of the eyes, and neurological effects such as dizziness.

Chronic (long-term) exposure to ethylbenzene by.